Should I get Rick's Central Europe guidebook in addition to this Prague & Czech Republic book?
Probably not. If your trip includes the Czech Republic as part of a wider trip to eastern central Europe — to Hungary, Slovakia, Croatia, Slovenia, and/or Poland — Rick Steves Central Europe is all you're likely to need. It includes thorough coverage of Rick's select picks in the Czech Republic (Prague, Prague's day trips, and Český Krumlov), albeit with less detail on Prague than you'll find in Rick Steves Prague & the Czech Republic, and without any coverage of central or eastern Czech Republic.
But if your big trip includes at least a week in the Czech Republic (or Czech destinations not covered in the bigger Central Europe book), the extra information in Rick Steves Prague can be worthwhile.
What's the difference between this Prague & the Czech Republic guidebook and Rick's Pocket Prague guide?
The biggest difference: The full-size Rick Steves Prague & the Czech Republic not only is a comprehensive guide to the Czech Republic's most exciting city, but also covers Rick's favorite Czech destinations beyond Prague.
Rick Steves Pocket Prague works best for people taking a short trip, or perhaps a return trip, to Prague — and not venturing beyond it. Like our other Pocket guides, Pocket Prague is smaller than the complete guidebook (and in full color), but still offers our best sightseeing advice and a handful of self-guided city walks and museum tours.
For travelers who want to delve deep into Prague, or travel elsewhere in the Czech Republic, the full-size guidebook is a better option. It offers complete chapters for plenty more Czech destinations, as well as more substantial (and more frequently updated) advice on Prague itself: practicalities, sightseeing, self-guided tours, hotels, restaurants, nightlife, shopping, and the city's history and culture.